Perlane is a dermal filler that was specially developed to correct moderate to severe facial wrinkles and folds, particularly those around the nose and mouth.

How Does It Work?

As we age, our skin loses some of its naturally occurring hyaluronic acid, a substance that contributes to skin’s fullness. Perlane helps restore that fullness by delivering hyaluronic acid particles into the skin via a clear biocompatible gel. The particles attract and bind to water molecules in the skin, thus restoring volume to the skin and reducing the appearance of deep wrinkles and folds.

What Facial Areas Does It Treat?

Perlane is primarily used to treat areas around the nose and mouth. This includes the nasolabial (or “laugh”) lines that run from the corners of the nose to the corners of the mouth, the pre-jowl sulcus ) (or “marionette”) lines that run from the corners of the mouth to the jawline, and “lipstick” lines above the upper lip.

What Is the Treatment Like?

The procedure is very quick—it typically takes less than 30 minutes. The filler will be injected into your skin in small amounts with an ultra-fine needle. Perlane contains a local anesthetic, lidocaine, which will help minimize any discomfort.

Do I Need to Plan for Any Recovery Time?

No. After the treatment, you can return immediately to your normal activities. You can expect, however, some slight redness, bruising, swelling and itching at the site of the injections. These minor side effects are usually gone within a few days.

In rare cases, small papules (red bumps) appear. These can be treated with an antibiotic. Be sure to call your physician if you develop papules—or if you’re concerned about any other side effect.

When Will I See Results—and How Long Will They Last?

You’ll notice some effects immediately, but it generally takes a week or two for the hyaluronic acid to fully bind with the water in your skin and fill out the targeted wrinkles.

The hyaluronic acid in Perlane is chemically cross-linked, a factor that keeps the filler from breaking down too fast. The effects of the filler last, therefore, for many months—typically, six to nine months.

In three clinical trials conducted by Perlane’s manufacturer, some 70 percent of 150 patients saw an improvement in the appearance of their wrinkles—an improvement that lasted for six months after their treatment.

Can Everybody Be Treated?

Almost everybody. Perlane should not be used by people with certain allergies (such as to lidocaine) or by people who have a bleeding disorder or who have recently taken blood-thinning medications.  Like other fillers, this one should also not be used on people with an active skin infection or inflammation. If you’re prone to herpes outbreaks, be sure to tell your physician, as he or she will want to make sure that this dermal filler treatment doesn’t trigger another outbreak.

During your consultation, your physician will review these and other counter-indications for treatment. Be sure, therefore, that you seek care from a physician experienced in the use of dermal fillers.

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